| QUANTITY | PRICE PER ITEM |
|---|---|
| 1 to 4 | $200.00 each |
| 5 to 9 | $180.00 each |
| 10 to + | $165.00 each |
Sermorelin (10mg)
Sermorelin is a synthetic peptide fragment composed of 29 amino acids, representing the functional N-terminal region (1–29) of endogenous human growth hormone–releasing hormone (GHRH). This truncated analogue retains the full biological activity of native GHRH, making it a potent GHRH receptor agonist. By binding to receptors on anterior pituitary somatotrophs, Sermorelin initiates physiologic, pulsatile growth hormone (GH) release, which subsequently stimulates the downstream IGF-1 axis.
In research contexts, Sermorelin is widely used as a tool for exploring GH regulation, pituitary responsiveness, and neuroendocrine signaling pathways. Because it mirrors the body’s natural hormone rhythms rather than overriding them, it provides a more physiological model for studying feedback control between GHRH, GH, somatostatin, and IGF-1.
Chemical Structure of Sermorelin
- Sequence (1–29 of human GHRH): Tyr–Ala–Asp–Ala–Ile–Phe–Thr–Asn–Ser–Tyr–Arg–Lys–Val–Leu–Gly–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Met–Ser–Arg–NH₂
- Modification: C-terminal amidation to enhance stability
- Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
- Molecular Weight: ~3,357.9 Da (PubChem CID: 16132413)
Research Applications and Effects
- GH–IGF-1 Axis Studies: Stimulates physiologic growth hormone pulses, allowing investigation of pituitary–hypothalamic regulation and endocrine feedback systems.
- Diagnostic Research Tool: Historically applied to assess pituitary function and evaluate somatotroph sensitivity in clinical and laboratory settings.
- Metabolic Investigations: Associated with changes in nitrogen retention, protein turnover, and markers of anabolic balance in research models.
- Neuroendocrine & Circadian Studies: Implicated in hypothalamic pathways influencing energy expenditure, orexin activity, and sleep-wake regulation.
Citations
- PubChem Compound Summary for Sermorelin (CID 16132413): full 29‑residue sequence; molecular formula C₁₄₉H₂₄₆N₄₄O₄₂S; MW 3,357.9 Da. Overview of Sermorelin
- Prakash A, Goa KL. “Sermorelin: a review of its use in diagnostics of GH deficiency.” BioDrugs. 1999;12(2):139–157. PMID: 10386610. Overview of Sermorelin
- Research on endogenous GH pulsatility with GHRH analogues like Sermorelin. J Clin Endocrinol Metab. Overview of Sermorelin
- Clinical endocrine studies: assessment of GH-axis modulation with Sermorelin. Endocrine Reviews. Overview of Sermorelin
- Preclinical studies on GHRH analogues and hypothalamic orexin signaling in metabolic regulation. Endocrinology. Overview of Sermorelin
Advanced Research Peptide: A highly stable synthetic heptapeptide designed for laboratory and academic research use.
High Purity & Stability: Built with the Pro-Gly-Pro (PGP) motif to resist enzymatic breakdown, enabling consistent results in experimental settings.
Neuroactive Properties: Its unique structure allows researchers to explore effects on neuroplasticity, gene expression, and molecular signaling pathways.
Molecular Precision: With a defined sequence (MEHFPGP) and confirmed molecular weight (813.9 Da), it offers reliability for controlled studies.
Versatile Application in Studies: Used to investigate areas such as cognitive processes, neurotransmitter activity, and cellular response to stress in preclinical models.
Backed by Published Research: Extensively studied in animal models and human volunteers for its influence on molecular and behavioral parameters (see citations).
We prioritize the highest safety standards for all our research products. Each compound is sourced from reputable laboratories and undergoes stringent quality checks before distribution. All items are intended strictly for in-vitro research purposes only and are not for human or animal consumption. Always handle these products using proper laboratory safety protocols.
Our products are produced and tested to ensure exceptional purity levels for research consistency. Every batch is analyzed using validated methods such as HPLC and mass spectrometry to confirm identity and quality. This rigorous approach ensures reliability and reproducibility in your scientific studies.
Always Quality-Tested, With proven results
Purity Verification
- Independent analysis confirming 99%+ purity for every batch.
Sterility Assurance
- Validated through sterile handling and testing protocols.
pH Balance Check
- Ensuring stability, consistency, and proper formulation standards.
Endotoxin Screening
- Rigorous checks to confirm compounds meet strict safety thresholds.
Why choose Elevated Vitality
Verified Purity
Every compound is third-party tested and verified 99%+ pure for consistency and reliability.
Made in USA
Manufactured under strict quality standards, ensuring trust and transparency at every step.
Transparent Pricing
No hidden fees, no subscriptions — straightforward access to premium formulations.
Seamless Experience
Fast, discreet shipping and a refined online ordering process designed for ease.
| Elevated Vitality Peptides | Typical Peptides Company | |
|---|---|---|
| Purity |
99%+ Verified Purity
|
Often Unverified
|
| Sourcing |
Made in USA, Strict Quality Controls
|
Overseas or Unclear Origins
|
| Transparency |
Clear Pricing, No Hidden Fees
|
Markups, Hidden Costs
|
| Standards |
Research-Driven, Lab-Tested
|
Limited Testing or Oversight
|
| Experience |
Luxury Packaging & Premium Support
|
Generic Presentation
|
| Trust |
Built On Integrity & Consistency
|
Little Brand Accountability
|
