| QUANTITY | PRICE PER ITEM |
|---|---|
| 1 to 4 | $200.00 each |
| 5 to 9 | $180.00 each |
| 10 to + | $165.00 each |
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondrial-derived peptide (MDP) composed of 16 amino acids, encoded within the mitochondrial 12S rRNA gene. Discovered as part of a novel class of bioactive peptides, MOTS-c has gained attention in research for its role in stress adaptation, metabolic regulation, and mitochondrial communication with the nucleus. Under conditions such as nutrient stress or physical activity, MOTS-c is expressed and can translocate to the nucleus, where it interacts with regulatory elements to fine-tune gene expression linked to energy and cellular homeostasis.
Chemical Structure of MOTS-c
- Sequence: Met–Arg–Trp–Gln–Glu–Met–Gly–Tyr–Ile–Phe–Tyr–Pro–Arg–Lys–Leu–Arg
- Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular Weight: ~2,174.6 Da
- Database Reference: PubChem CID 255386757
Research Insights and Applications
- Metabolic Regulation: MOTS-c has been studied for its ability to activate the AICAR–AMPK pathway, which plays a central role in glucose uptake, fatty acid oxidation, and overall energy balance in preclinical models.
- Insulin and Glucose Dynamics: In animal studies, MOTS-c has been observed to improve glucose tolerance and insulin sensitivity, making it a subject of research in metabolic health investigations.
- Mitochondrial Performance and Endurance: MOTS-c has been linked to enhanced exercise capacity and muscle performance in rodent models, suggesting a role in mitochondrial biogenesis and physical resilience.
- Cardiovascular and Cellular Stress Response: Research indicates MOTS-c supports vascular health and mitochondrial recovery through AMPK-mediated pathways.
- Aging and Longevity Research: Levels of endogenous MOTS-c decline with age, and supplementation in experimental models has been connected to improvements in resilience, energy regulation, and fitness over time.
Advanced Research Peptide: A highly stable synthetic heptapeptide designed for laboratory and academic research use.
High Purity & Stability: Built with the Pro-Gly-Pro (PGP) motif to resist enzymatic breakdown, enabling consistent results in experimental settings.
Neuroactive Properties: Its unique structure allows researchers to explore effects on neuroplasticity, gene expression, and molecular signaling pathways.
Molecular Precision: With a defined sequence (MEHFPGP) and confirmed molecular weight (813.9 Da), it offers reliability for controlled studies.
Versatile Application in Studies: Used to investigate areas such as cognitive processes, neurotransmitter activity, and cellular response to stress in preclinical models.
Backed by Published Research: Extensively studied in animal models and human volunteers for its influence on molecular and behavioral parameters (see citations).
We prioritize the highest safety standards for all our research products. Each compound is sourced from reputable laboratories and undergoes stringent quality checks before distribution. All items are intended strictly for in-vitro research purposes only and are not for human or animal consumption. Always handle these products using proper laboratory safety protocols.
Our products are produced and tested to ensure exceptional purity levels for research consistency. Every batch is analyzed using validated methods such as HPLC and mass spectrometry to confirm identity and quality. This rigorous approach ensures reliability and reproducibility in your scientific studies.
Always Quality-Tested, With proven results
Purity Verification
- Independent analysis confirming 99%+ purity for every batch.
Sterility Assurance
- Validated through sterile handling and testing protocols.
pH Balance Check
- Ensuring stability, consistency, and proper formulation standards.
Endotoxin Screening
- Rigorous checks to confirm compounds meet strict safety thresholds.
Why choose Elevated Vitality
| Elevated Vitality Peptides | Typical Peptides Company | |
|---|---|---|
| Purity |
99%+ Verified Purity
|
Often Unverified
|
| Sourcing |
Made in USA, Strict Quality Controls
|
Overseas or Unclear Origins
|
| Transparency |
Clear Pricing, No Hidden Fees
|
Markups, Hidden Costs
|
| Standards |
Research-Driven, Lab-Tested
|
Limited Testing or Oversight
|
| Experience |
Luxury Packaging & Premium Support
|
Generic Presentation
|
| Trust |
Built On Integrity & Consistency
|
Little Brand Accountability
|




