| QUANTITY | PRICE PER ITEM |
|---|---|
| 1 to 4 | $200.00 each |
| 5 to 9 | $180.00 each |
| 10 to + | $165.00 each |
What is HCG (5000 IU)?
Human Chorionic Gonadotropin (HCG) is a naturally occurring glycoprotein hormone produced by the placenta during pregnancy. It exerts its activity through the luteinizing hormone/choriogonadotropin receptor (LHCGR), where it serves as a potent agonist. Structurally, HCG is a disulfide-rich heterodimer, composed of an α-subunit shared with other glycoprotein hormones (LH, FSH, TSH) and a β-subunit unique to HCG. This structural design provides receptor specificity and extends its biological half-life, making HCG a distinct regulator of reproductive and endocrine signaling pathways in research.
Chemical Structure of HCG
- Type: Heterodimeric glycoprotein hormone
- Molecular weight: ~37.9 kDa
- Composition: ~30% carbohydrate by weight
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Subunits:
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Alpha (α) subunit: 92 amino acids, common across LH, FSH, TSH, and HCG
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Beta (β) subunit: 145 amino acids with a unique 24-residue C-terminal peptide (CTP) that prolongs its half-life
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- Glycosylation: Eight carbohydrate chains — 2 N-linked on α, plus 2 N-linked and 4 O-linked on β — enhancing structural stability and circulating persistence
- Cystine-knot motif: Six disulfide bonds across both subunits create a rigid 3D fold essential for receptor binding and signaling
Research Applications of HCG
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LHCGR Signaling
HCG binding initiates Gs and Gq protein pathways, resulting in cAMP generation and downstream steroidogenic responses in gonadotropin-sensitive cells. -
Angiogenic and Paracrine Roles
In vitro studies indicate that HCG can stimulate endothelial activity, promoting the release of angiogenic mediators such as VEGF. -
Reproductive Endocrinology
Research demonstrates HCG’s role in enhancing progesterone release and supporting oocyte maturation, highlighting its influence on granulosa cell activity. -
Biased Agonism
Compared to LH, HCG exhibits differential kinetics at the LHCGR, modulating cAMP production and gene expression in unique ways.Citations
- RCSB PDB – “Structure of human chorionic gonadotropin at 2.6 Å resolution” Overview of HCG Structure and Receptor Interaction
- Sigma-Aldrich – “Human chorionic gonadotropin (HCG): glycoprotein heterodimer overview” Overview of HCG Structure and Receptor Interaction
- Frontiers in Immunology – “HCG induces angiogenic responses via LHCGR activation” Overview of HCG Structure and Receptor Interaction
- MDPI Int. J. Mol. Sci. – “HCG promotes oocyte maturation and embryo development” Overview of HCG Structure and Receptor Interaction
- Reproductive Biology and Endocrinology – “Biological functions of HCG variants” Overview of HCG Structure and Receptor Interaction
- Cell/Structure – “Three-dimensional structure of HCG reveals cystine-knot fold” Overview of HCG Structure and Receptor Interaction
Advanced Research Peptide: A highly stable synthetic heptapeptide designed for laboratory and academic research use.
High Purity & Stability: Built with the Pro-Gly-Pro (PGP) motif to resist enzymatic breakdown, enabling consistent results in experimental settings.
Neuroactive Properties: Its unique structure allows researchers to explore effects on neuroplasticity, gene expression, and molecular signaling pathways.
Molecular Precision: With a defined sequence (MEHFPGP) and confirmed molecular weight (813.9 Da), it offers reliability for controlled studies.
Versatile Application in Studies: Used to investigate areas such as cognitive processes, neurotransmitter activity, and cellular response to stress in preclinical models.
Backed by Published Research: Extensively studied in animal models and human volunteers for its influence on molecular and behavioral parameters (see citations).
We prioritize the highest safety standards for all our research products. Each compound is sourced from reputable laboratories and undergoes stringent quality checks before distribution. All items are intended strictly for in-vitro research purposes only and are not for human or animal consumption. Always handle these products using proper laboratory safety protocols.
Our products are produced and tested to ensure exceptional purity levels for research consistency. Every batch is analyzed using validated methods such as HPLC and mass spectrometry to confirm identity and quality. This rigorous approach ensures reliability and reproducibility in your scientific studies.
Always Quality-Tested, With proven results
Purity Verification
- Independent analysis confirming 99%+ purity for every batch.
Sterility Assurance
- Validated through sterile handling and testing protocols.
pH Balance Check
- Ensuring stability, consistency, and proper formulation standards.
Endotoxin Screening
- Rigorous checks to confirm compounds meet strict safety thresholds.
Why choose Elevated Vitality
| Elevated Vitality Peptides | Typical Peptides Company | |
|---|---|---|
| Purity |
99%+ Verified Purity
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Often Unverified
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| Sourcing |
Made in USA, Strict Quality Controls
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Overseas or Unclear Origins
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| Transparency |
Clear Pricing, No Hidden Fees
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Markups, Hidden Costs
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| Standards |
Research-Driven, Lab-Tested
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Limited Testing or Oversight
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| Experience |
Luxury Packaging & Premium Support
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Generic Presentation
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| Trust |
Built On Integrity & Consistency
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Little Brand Accountability
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